Capecitabine

Common name: Capecitabine
commodity name: Xeloda
Chemical name: 5'-Deoxy-5-Fluoro-N-[(Pentyloxy)Carbonyl]Cytidine
Molecular formula: C15H22O6N3F
Cas No.: 154361-50-9
Molecular weight:359.35
Assay content  : 99.0%min
Moisture content: 1.0% max
related matter : 0.5% max
Capecitabine (INN) (Xeloda, Roche) is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil.

Post Date:	8/14/2009
Expiry Date:	8/9/2010