St. John's Wort Plant Extract (St. John's Wort Plant Extract)

Main Active IgredientsThe most active ingredients is the hypericins and hyperforins in St. John's Wort. Include Hypericin Pseudohypericin Prtohypericin, Protopseudohypericin Cyclopseudohypericin Isohypercin Emodin-anthrone Hypericode-hydrodianthrone Hyperforin and Adhyperforin.Also there are many other compound in the St. John's Wort, flavonoids like Hyperin(Hyperoside), organic acid and so on.
Hypericin is a photochemical extracted from St. Johns Wort (Hypericum perforatum) and related species, has been shown to have potent, broad spectrum antimicrobial activity. This compound is an aromatic polycyclic anthrone, a class of colored or pigmented chemical substances which have photosensitizing activity. In both in vitro (laboratory) and in vivo (animal) studies, low, non-toxic doses of hypericin significantly inhibited the replication of several viruses, including HIV, influenza A, cytomegalovirus (CMV), Herpes simplex 1 and 2 (HSV-1 and HSV-2), and Epstein-Barr virus (EBV). Hypericin and its chemical relative, pseudohypericin, produce antiviral activity through a different mechanism of action than do AZT and other nucleoside antiviral agents. Hypericin does not appear to directly alter the activity of reverse transcriptase although it does block the formation of HIV synctium. Recent findings have shown that the antiretroviral action of this compound disrupts uncoating of the lipid envelope of both DNA and RNA viruses, thus preventing infected cells from releasing HIV copies. Theoretically, hypericin and AZT, in combination, may have synergistic antiviral effects against HIV. On the other hand, hypericin actually may increase the toxicity of antiretroviral nucleosides such as AZT, ddI, or ddC.
Hyperforin is a derivative of St. Johns Wort and may be partially responsible for its positive health benefits. Clinical studies show that the cumulative action of hyperforin, hypericin, ad-hyperforin and flavonoids may help to influence the availability of neurotransmitters like serotonin and norepinephrine. Although research into how St. Johns Wort works is still being performed, this mechanism of action is believed to be responsible for St. Johns Wort's mood enhancing effects.
Specification1. Hypericins 0.3% Test by UV2. Hypericin 0.3% Test by HPLC3. Hypericin 0.3% Hyperforin 1%-5% Test by HPLC