Asiaron Chemical Limited| Manufacturer

Asiaron Chemical Limited

[ Shanghai, China ]
Business Type: Manufacturer
Main Product: Aromatics, Nutritional ingredients
Year Established: 1900
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Asiaron Chemical Limited

China Manufacturer with main products: Aromatics, Nutritional ingredients

Home  >Products Catalog > Niacinamide (Vitamin B3 / Vitamin PP)

Niacinamide (Vitamin B3 / Vitamin PP)


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Place of Origin: Shanghai in China

Specifications

Niacinamide / Nicotinamide
(Vitamin B3 / Vitamin PP)
Nicotinamide, also known as niacinamide and nicotinic acid amide, is the amide of nicotinic acid (vitamin B3). Nicotinamide is a water-soluble vitamin and is part of the vitamin B group.

Nicotinamide has demonstrated anti-inflammatory actions which may be of benefit in patients with inflammatory skin conditions. These conditions include acne vulgaris, and the compound can suppress antigen induced-lymphocytic transformation and inhibit of 3'-5' cyclic AMP phosphodiesterase. Nicotinamide has demonstrated the ability to block the inflammatory actions of iodides known to precipitate or exacerbate inflammatory acne.

Animal studies show that nicotinamide has anti-anxiety (anxiolytic) properties. It may work in a way similar to benzodiazepines.

Nicomide (take note the naming similarity), is an acne medication, and in its vitamin supplement form, the most predominant ingredient is 750 mg of nicotinamide, based on this area of research.

Nicotinamide lacks the vasodilator, gastrointestinal, hepatic, and hypolipemic actions of nicotinic acid. As such nicotinamide has not been shown to produce the flushing, itching and burning sensations of the skin as is commonly seen when large doses of nicotinic acid are administered orally. However, nicotinamide can produce liver toxicity at high doses.[6] In overall, it rarely causes side effects, and is considered generally safe as a food additive, component in cosmetics and medication.[7]

Nicotinamide is produced by the aqueous ammonolysis of 3-cyanopyridine (nicotinonitrile) and subsequent crystallisation.

 

  • Basic information
    Item
    Index
    Chemical Name
    3-Pyridinecarboxamide; Nicotinamide; Propamine A; モ-Pyridinecarboxamide; Nicosylamide; Nicotamide; Nicotilamide; Nicotine acid amide; Nicotinic acid amide; Nicotinic amide; Nicotylamide; Nicovit; Nicovitina; Nikotinamid; Niocinamide; 3-carbamoyl-Pyridine; Vitamin B; Vitamin B3; 3-Carbamoylpyridine; 3-Pyridinecarboxylic acid amide; Picolinamide; Niamide; Nicamide; Nicogen; Nicomidol; Nicota; Nicotililamido; Nicotinsaureamid; Nicotol; Nicovel; Nicovitol; Nicozymin; Vitamin PP; Witamina PP; Amid kyseliny nikotinove; Amnicotin; Norcholine; Amid Kyseliny Nikotinove (Czech); M-(Aminocarbonyl)Pyridine; Delonin Amide; Nicotinsaureamid (German); Nikotinsaeureamid (German); 
    Molecular Formula
    C6H6N2O
    Chemical Structure
                            
    Molecular Weight
    122.13
    CAS No.
    98-92-0
    EINECS NO.
    202-713-4
    Physical Properties
    White or yellowish crystal or crystalline powder, odorless or slightly odoriferous, bitter taste, easily soluble in water or ethanol and soluble in glycerol
    Stability
    Stable under ordinary conditions
    NFPA rating
    Health: 1 Flammability: 1 Reactivity: 0
    Application
    feed additive, pharmaceuticals, food enrichment, animal mixes for livestock
     
  • USP29
    In conformity with the standard of USP29
    Item
    Index
    Appearance
    white crystalline powder
    Solubility
    Complies
    Readily Carbonizable Substances
    Complies
    Identification
    Complies
    Organic Volatile Impurities
    Complies
    Assay [C6H6N2O], %
    98.5-101.5
    Melting Point, ℃
    128-131
    Loss on Drying, %
    0.5 max.
    Heavy Metals, %
    0.003 max.
    Residue on Ignition, %
    0.1 max.
     
  • BP2003
    In conformity with the standard of BP2003
    Item
    Index
    Appearance
    white crystalline powder
    Solubility
    Complies
    Related Substances
    Complies
    Identification
    Complies
    Assay [C6H6N2O], %
    99.0-101.0
    Melting Point, ℃
    128-131
    PH
    6.0-7.5
    Loss on Drying, %
    0.5 max.
    Heavy Metals, %
    0.003 max.
    Sulphated Ash, %
    0.1 max.
     
  • GB7301-87
    In conformity with the standard of GB7301-87
    Item
    Index
    Appearance
    white crystalline powder
    Solubility
    Complies
    Identification
    Complies
    Assay [C6H6N2O], %
    98.5-101.0
    Melting Point, ℃
    128-131
    PH
    5.5-7.5
    Loss on Drying, %
    0.5 max.
    Heavy Metals, %
    0.002 max.
    Residue on Ignition, %
    0.1 max.
     
  • Packing
    In 25Kg/drum or 20Kg/carton net each

     
  • Dosage
    15-30mg /kg in swine,30-60mg /kg in broilers, 30-40mg /kg in calves (milk replacer), 60-80mg /kg in turkeys, 50-80mg /kg in fish.

     
  • Period of validity
    2years

Service Process

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